Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035359 | 0.87 | LMNA (0.72) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9437305 | 0.84 | DPP4 (0.58) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11277560 | 0.81 | LMNA (0.59) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10521403 | 0.81 | LMNA (0.70) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11092618 | 0.79 | LMNA (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11089508 | 0.78 | KDM4E (0.51) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL18213620 | 0.78 | LMNA (0.65) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11714386 | 0.77 | SMN1; SMN2 (0.44) | LMNACYP2C9ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11269349 | 0.77 | LMNA (0.52) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9437310 | 0.77 | DPP4 (0.50) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382937-A | Naphthyridine derivatives and their use as anti-bacterials | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| US-4359578-A | Naphthyridine derivatives and salts thereof useful as antibacterial agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-11-16 | — | — | US | disclosed |
| US-4352803-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0009425-B1 | NOVEL NAPHTYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1982-01-27 | — | — | EP | disclosed |
| EP-0009425-A1 | Novel naphtyridine derivatives and pharmaceutical compositions containing them | Société anonyme dite: LABORATOIRE ROGER BELLON (FR) | 1980-04-02 | — | — | EP | disclosed |