Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11220134 | 0.91 | ELANE (0.42) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11200460 | 0.90 | MAPK1 (0.35) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11201461 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11215394 | 0.83 | PRKCI (0.42) | ELANE | |
| SCHEMBL11205729 | 0.81 | KDM4E (0.33) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11197939 | 0.78 | HCRTR1 (0.49) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11200451 | 0.78 | LMNA (0.38) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11203490 | 0.77 | ELANE (0.36) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11204206 | 0.76 | HTR2A (0.34) | KDM4EALDH1A1MAPK1ELANEHCRTR1 | |
| SCHEMBL11207434 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |