Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200670 | 0.91 | KDM4E (0.36) | ELANEALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL11200460 | 0.88 | MAPK1 (0.35) | ELANEALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL11201461 | 0.87 | KDM4E (0.39) | ELANEALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL11205301 | 0.82 | PRKCI (0.43) | ELANEHTR2ASMN1; SMN2KHK | |
| SCHEMBL11197939 | 0.80 | HCRTR1 (0.49) | ALDH1A1L3MBTL1KDM4EMAPTMAPK1 | |
| SCHEMBL11200451 | 0.80 | LMNA (0.38) | ELANEALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL11205729 | 0.78 | KDM4E (0.33) | ALDH1A1L3MBTL1KDM4EMAPTMAPK1 | |
| SCHEMBL11207434 | 0.78 | KDM4E (0.38) | ELANEALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL11198545 | 0.78 | HRH4 (0.42) | ALDH1A1L3MBTL1KDM4EMAPTMAPK1 | |
| SCHEMBL11202884 | 0.77 | HCRTR1 (0.47) | ALDH1A1L3MBTL1KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |