Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16587378 | 0.87 | MEN1 (0.59) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL6765925 | 0.76 | ALDH1A1 (0.65) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL10202166 | 0.75 | ALDH1A1 (0.58) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL4822650 | 0.72 | MEN1 (0.65) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL699925 | 0.72 | MEN1 (0.71) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL9532375 | 0.72 | ALDH1A1 (0.50) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL3565748 | 0.70 | ALDH1A1 (0.57) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL14817549 | 0.70 | ALDH1A1 (0.61) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| Phenylthioacetylglycine SCHEMBL11381408 | 0.70 | AKR1B1 (0.54) | KMT2AMEN1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL19371412 | 0.70 | RAB9A (0.70) | KMT2AMEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394520-A | SKIN DISORDERS | SOCIETE ANONYME DITE: L'OREAL (FR) | 1983-07-19 | — | — | US | disclosed |
| US-4204064-A | FOR TREATMENT OF SKIN OR SCALP | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4085217-A | DERIVATIVES OF CYSTEINE OR CYSTEAMINE | L'OREAL (FR) | 1978-04-18 | — | — | US | disclosed |
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | disclosed |