SCHEMBL16587378

SCHEMBL16587378

O=C(Cc1ccccc1)NC(=S)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
ALDH1A1 P00352 5/20 0.58
LMNA P02545 2/20 0.58
EPHX2 P34913 1/20 0.55
GAA P10253 3/20 0.53
CRHBP P24387 1/20 0.51
NPBWR1 P48145 1/20 0.51
CRHR2 Q13324 1/20 0.51
MCHR1 Q99705 1/20 0.51
RAB9A P51151 1/20 0.51
MAPT P10636 2/20 0.50
POLB P06746 2/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
AKR1B1 P15121 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10202166 0.87 ALDH1A1 (0.58) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL11200673 0.87 KMT2A (0.48) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL699925 0.85 MEN1 (0.71) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL3565748 0.82 ALDH1A1 (0.57) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL14817549 0.82 ALDH1A1 (0.61) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL6470572 0.81 MEN1 (0.65) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL171909 0.79 CRHBP (0.58) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL15145920 0.79 GAA (0.71) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL13664094 0.78 ALDH1A1 (0.56) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL20133828 0.78 ALDH1A1 (0.56) MEN1KMT2AHDAC8HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed