SCHEMBL11200795

SCHEMBL11200795

C=CCS(=O)(=O)Cc1nccc(O)n1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27688088 0.78 KDM4E (0.38) KDM4E
SCHEMBL532603 0.74 XDH (0.34) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL11346651 0.71 PIK3CA (0.32) KMT2A
SCHEMBL3545689 0.69 TLR8 (0.38) ALDH1A1LMNAL3MBTL1
SCHEMBL10892732 0.68 ALOX5 (0.32) MEN1KMT2A
SCHEMBL11773992 0.66 ALDH1A1 (0.42) ALDH1A1KDM4ELMNAMAPTKMT2A
SCHEMBL27475724 0.66
SCHEMBL24243015 0.64
SCHEMBL9474935 0.64
SCHEMBL2633102 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022511-B1 O-PYRIMIDINYL ESTERS OF N,N-DIMETHYL CARBAMIC ACID, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS PARASITICIDES BAYER AG (DE) 1983-03-09 EP disclosed