Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861659 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAHPGDDAO | |
| SCHEMBL2070913 | 0.72 | CRHR1 (0.37) | KDM4ELMNAMEN1RAB9AKMT2A | |
| SCHEMBL27250753 | 0.71 | CYP1A2 (0.41) | ALDH1A1KDM4EPTGS2SLC22A12HPGD | |
| SCHEMBL2070835 | 0.69 | RXFP1 (0.37) | ALDH1A1KDM4ELMNAMEN1NPC1 | |
| SCHEMBL11491285 | 0.67 | RXFP1 (0.36) | ALDH1A1KDM4ELMNAMEN1NPC1 | |
| SCHEMBL15026014 | 0.64 | HPGDS (0.44) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL676678 | 0.64 | HPGDS (0.56) | NPC1RAB9APTGS2PIK3CAHPGDS | |
| SCHEMBL11203629 | 0.64 | KLKB1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22932832 | 0.64 | KDM4E (0.51) | ALDH1A1KDM4ELMNAMEN1NPC1 | |
| SCHEMBL10986060 | 0.64 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083186-A2 | Thiazole derivatives as H2-receptor antagonists | ELI LILLY AND COMPANY (US) | 1983-07-06 | — | — | EP | disclosed |