Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202820 | 0.92 | NR3C1 (0.78) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Water SCHEMBL11200345 | 0.91 | NR3C1 (0.76) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| Water SCHEMBL11200349 | 0.91 | NR3C1 (0.76) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL8495619 | 0.88 | PDE3B (0.85) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11192867 | 0.86 | KCNH2 (0.58) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11202917 | 0.85 | PDE3B (0.57) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL8499623 | 0.85 | PDE3B (0.69) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11042441 | 0.83 | NR3C1 (0.66) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11200540 | 0.82 | NR3C1 (0.54) | NR3C1PGRSLC6A4KCNH2PDE3B | |
| SCHEMBL11196576 | 0.81 | KCNH2 (0.69) | NR3C1PGRSLC6A4KCNH2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |