Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957551 | 0.87 | ALDH1A1 (0.42) | KDM4EALDH1A1ADRA2CGAAMAPT | |
| SCHEMBL11197597 | 0.68 | CDC42 (0.40) | KDM4EALDH1A1ADRA2CGAAMAPT | |
| SCHEMBL26439682 | 0.67 | ALDH1A1 (0.40) | KDM4EALDH1A1ADRA2CGAAMAPT | |
| SCHEMBL11194418 | 0.64 | ADRA2C (0.40) | KDM4EALDH1A1ADRA2CMAPT | |
| SCHEMBL11201877 | 0.62 | CDC42 (0.41) | KDM4EALDH1A1ADRA2CGAAMAPT | |
| SCHEMBL27977488 | 0.62 | — | — | |
| SCHEMBL14160426 | 0.61 | ALDH1A1 (0.81) | KDM4EALDH1A1ADRA2CGAAMAPT | |
| SCHEMBL11490694 | 0.60 | MITF (0.37) | KDM4EALDH1A1ADRA2CMAPT | |
| Hydrochloric Acid SCHEMBL4780681 | 0.60 | ALDH1A1 (0.79) | KDM4EALDH1A1ADRA2CGAAMAPT | |
| SCHEMBL2560148 | 0.60 | KDM4E (0.34) | KDM4EALDH1A1ADRA2CGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |