Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93210 | 0.89 | SLC6A3 (0.41) | TSHRLMNAHTR2AHTR2CHTR2B | |
| SCHEMBL4385331 | 0.85 | SLC6A2 (0.44) | HTR2AHTR2CHTR2BGAAKMT2A | |
| SCHEMBL14155985 | 0.85 | SLC6A2 (0.44) | HTR2AHTR2CHTR2BGAAKMT2A | |
| SCHEMBL18504403 | 0.84 | TSHR (0.43) | TSHRLMNAHTR2AHTR2CHTR2B | |
| SCHEMBL23376906 | 0.82 | SMN1; SMN2 (0.42) | TSHRLMNAHTR2AHTR2CHTR2B | |
| SCHEMBL30064748 | 0.82 | EPHX1 (0.40) | TSHRHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL231069 | 0.78 | — | — | |
| SCHEMBL1498876 | 0.77 | HTR2A (0.42) | TSHRLMNAHTR2AHTR2CHTR2B | |
| SCHEMBL4087354 | 0.77 | SLC5A2 (0.43) | TSHRLMNAHTR2AHTR2CHTR2B | |
| SCHEMBL4077173 | 0.77 | SLC5A2 (0.43) | TSHRLMNAHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4413003-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1983-11-01 | — | — | US | disclosed |