Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 3/20 | 0.46 |
| ▸ | SELE | P16581 | 3/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206009 | 0.86 | SELE (0.46) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL11197736 | 0.86 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL5114669 | 0.83 | ICAM1 (0.66) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL11205856 | 0.83 | MEN1 (0.53) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL11200152 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL11207331 | 0.82 | ALDH1A1 (0.56) | KDM4EALDH1A1HSD17B10PRKCICYP1A2 | |
| SCHEMBL5118432 | 0.81 | ICAM1 (0.48) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL5119424 | 0.81 | ICAM1 (0.51) | KDM4EALDH1A1HSD17B10PRKCISELE | |
| SCHEMBL1970286 | 0.79 | SELE (0.60) | KDM4EALDH1A1HSD17B10SELEVCAM1 | |
| SCHEMBL5123734 | 0.77 | APP (0.48) | SELEVCAM1ICAM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |