Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PRKCI | P41743 | 3/20 | 0.45 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197736 | 0.85 | KDM4E (0.64) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11201183 | 0.82 | KDM4E (0.49) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11205856 | 0.79 | MEN1 (0.53) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11206009 | 0.77 | SELE (0.46) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11198709 | 0.77 | HRH4 (0.48) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL5114669 | 0.74 | ICAM1 (0.66) | ALDH1A1KDM4EHSD17B10MEN1CYP1A2 | |
| SCHEMBL11200152 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL5119424 | 0.72 | ICAM1 (0.51) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL5118432 | 0.72 | ICAM1 (0.48) | ALDH1A1KDM4EHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL10836929 | 0.72 | CYP1A2 (0.70) | ALDH1A1KDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |