Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942937 | 0.90 | ACHE (0.52) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL28337010 | 0.86 | PPARA (0.62) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL31539531 | 0.85 | CYP4F2 (0.54) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL1789805 | 0.84 | PPARA (0.56) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL11206161 | 0.83 | ACHE (0.51) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL27864662 | 0.83 | ACHE (0.56) | ACHE | |
| SCHEMBL11201205 | 0.81 | ACHE (0.49) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL28593564 | 0.81 | ACHE (0.58) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL11197529 | 0.80 | CHRM2 (0.58) | PPARAPPARGCYP2D6 | |
| SCHEMBL9627105 | 0.80 | CHRM2 (0.56) | MTNR1AMTNR1BHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |