Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200140 | 0.88 | MGLL (0.58) | MGLLHPGDLMNAALDH1A1MAPT | |
| SCHEMBL11196441 | 0.88 | PDE3B (0.60) | PDE3BPDE3AC1SMGLLLMNA | |
| SCHEMBL11205029 | 0.85 | NAMPT (0.48) | PDE3BPDE3AHTR1ASLC6A2SLC6A3 | |
| SCHEMBL11197233 | 0.85 | POLB (0.59) | PDE3BPDE3ALMNAALDH1A1GAA | |
| SCHEMBL11197911 | 0.84 | MGLL (0.60) | MGLLLMNAALDH1A1GAAMAPT | |
| SCHEMBL11200241 | 0.81 | ALDH1A1 (0.61) | HPGDLMNAALDH1A1GAAMAPT | |
| SCHEMBL8500022 | 0.81 | PDE3B (0.65) | PDE3BPDE3ALMNAALDH1A1GAA | |
| SCHEMBL11193805 | 0.81 | SMN1; SMN2 (0.57) | PDE3BPDE3AMGLLLMNAUSP2 | |
| SCHEMBL9412127 | 0.80 | ALDH1A1 (0.56) | PDE3BPDE3AMGLLALDH1A1MAPT | |
| SCHEMBL11201118 | 0.79 | PDE3B (0.55) | PDE3BPDE3ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |