Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 3/20 | 0.31 |
| ▸ | EPHA3 | P29320 | 3/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202902 | 0.92 | HCRTR1 (0.38) | HCRTR1HCRTR2KDM4EALDH1A1MAPK1 | |
| SCHEMBL11200715 | 0.84 | HRH4 (0.34) | KDM4EALDH1A1MAPK1MAPTL3MBTL1 | |
| SCHEMBL11200986 | 0.82 | IKBKB (0.43) | KDM4EALDH1A1MAPTHRH4IKBKB | |
| SCHEMBL11197939 | 0.82 | HCRTR1 (0.49) | HCRTR1HCRTR2KDM4EALDH1A1MAPK1 | |
| SCHEMBL11202884 | 0.79 | HCRTR1 (0.47) | HCRTR1HCRTR2KDM4EALDH1A1MAPK1 | |
| SCHEMBL11201993 | 0.79 | HCRTR1 (0.37) | HCRTR1HCRTR2KDM4EALDH1A1MAPK1 | |
| SCHEMBL11201197 | 0.77 | LMNA (0.38) | KDM4EALDH1A1MAPK1MAPTL3MBTL1 | |
| SCHEMBL11205773 | 0.76 | HRH4 (0.36) | KDM4EALDH1A1MAPK1MAPTL3MBTL1 | |
| SCHEMBL11203700 | 0.76 | KDM4E (0.34) | KDM4EALDH1A1MAPK1MAPTL3MBTL1 | |
| SCHEMBL11202798 | 0.75 | HTR6 (0.37) | HCRTR1HCRTR2KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |