Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846802 | 0.84 | GCK (0.46) | GCKNPC1KDM4EALDH1A1CASP1 | |
| SCHEMBL9680968 | 0.83 | KDM4E (0.43) | GCKMEN1NPC1KMT2AKDM4E | |
| SCHEMBL10848909 | 0.82 | GAA (0.52) | GCKCASP1 | |
| SCHEMBL9365456 | 0.80 | NPC1 (0.43) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL11002896 | 0.78 | MAPT (0.47) | NPC1KDM4EALDH1A1CASP1 | |
| SCHEMBL10999376 | 0.77 | MAPT (0.44) | GCKNPC1KDM4EALDH1A1CASP1 | |
| SCHEMBL27500934 | 0.76 | RXFP1 (0.45) | MEN1NPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10388680 | 0.75 | THRB (0.52) | — | |
| SCHEMBL10994300 | 0.75 | ALDH1A1 (0.41) | GCKMEN1KMT2AALDH1A1CASP1 | |
| SCHEMBL10994307 | 0.75 | ALDH1A1 (0.41) | GCKMEN1KMT2AALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58124707-A | — | — | None | — | — | JP | disclosed |
| JP-S58124707-A | HERBICIDE | NIPPON TOKUSHU NOYAKU SEIZO KK | 1983-07-25 | — | — | JP | disclosed |