Valine

Valine

SCHEMBL7645312

CC(C)[C@H](N)C(=O)O.O=C(Cl)Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.50
SLC1A3 P43003 4/20 0.49
SLC1A2 P43004 4/20 0.49
SLC1A1 P43005 4/20 0.49
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
TSHR P16473 1/20 0.45
SLC15A1 P46059 1/20 0.45
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
AKR1B1 P15121 1/20 0.42
SLC6A2 P23975 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL11201581 0.86 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Phenylacetic Acid SCHEMBL8902802 0.86 AKR1B1 (0.61) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Diphenylmethane SCHEMBL2494259 0.82 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL27680015 0.81 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL4726209 0.81 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Valine SCHEMBL4716541 0.81 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2SLC1A1MEN1
Ethane SCHEMBL10956080 0.80 CES1 (0.58) MEN1KMT2ATSHRPTGS1CES2
Methyl Alcohol SCHEMBL3883089 0.80 CES1 (0.58) MEN1KMT2ATSHRPTGS1CES2
SCHEMBL27293995 0.80 CES1 (0.64) MEN1CYP2C9KMT2ATSHRPTGS1
SCHEMBL1493 0.80 CES1 (0.64) MEN1CYP2C9KMT2ATSHRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6451734-B1 Substituted 3-benzylpyrazoles and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2002-09-17 US disclosed