Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357932 | 0.79 | ALDH1A1 (0.69) | CYP3A4TDP1ALDH1A1HPGDTRPV4 | |
| SCHEMBL7525499 | 0.77 | ALDH1A1 (0.54) | CYP3A4TDP1ALDH1A1HPGDTRPV4 | |
| SCHEMBL11528908 | 0.75 | TDP1 (0.42) | CYP3A4TDP1ALDH1A1HPGDTRPA1 | |
| SCHEMBL11471789 | 0.75 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1HPGDTRPA1 | |
| SCHEMBL10816156 | 0.73 | ALDH1A1 (0.45) | CYP3A4TDP1ALDH1A1HPGDKDM4E | |
| SCHEMBL10939587 | 0.72 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1HPGDTRPA1 | |
| SCHEMBL29648862 | 0.72 | RAB9A (0.40) | CYP3A4TDP1ALDH1A1HPGDTRPA1 | |
| SCHEMBL162277 | 0.72 | RAB9A (0.40) | CYP3A4TDP1ALDH1A1HPGDTRPA1 | |
| SCHEMBL29648775 | 0.71 | CYP3A4 (0.49) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL160585 | 0.71 | CYP3A4 (0.49) | CYP3A4TDP1ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069855-A2 | N-(2-fluoro-4-halo-5-substituted phenyl)hydantoins, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-01-19 | — | — | EP | disclosed |