Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932117 | 0.79 | LMNA (0.50) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL5932119 | 0.79 | LMNA (0.50) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL9799692 | 0.77 | RAB9A (0.41) | SMN1; SMN2RAB9ANPC1HPGDELANE | |
| SCHEMBL28367963 | 0.77 | ELANE (0.42) | SMN1; SMN2RAB9ANPC1HPGDELANE | |
| SCHEMBL3868467 | 0.77 | HDAC1 (0.52) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL3868471 | 0.77 | HDAC1 (0.52) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL377478 | 0.77 | HDAC1 (0.52) | SMN1; SMN2RAB9ANPC1HDAC3HDAC4 | |
| SCHEMBL465525 | 0.77 | HDAC1 (0.52) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC2 | |
| Styrene SCHEMBL990787 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2RAB9ANPC1HPGDELANE | |
| SCHEMBL27499907 | 0.75 | HDAC1 (0.50) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018531-B1 | SUBSTITUTED 2,2-DIMETHYLPENTANE (ENE)-1-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF STYRYL-CYCLOPROPANE-CARBOXYLATES | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0018531-A1 | Substituted 2,2-dimethylpentane (ene)-1-carboxylic acid derivatives, process for their preparation and their use for the preparation of styryl-cyclopropane-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |