Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | FABP3 | P05413 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10944390 | 1.00 | CA2 (0.39) | CA2CES2CES1FABP3CA1 | |
| Acetic Acid SCHEMBL1268601 | 1.00 | CA2 (0.39) | CA2CES2CES1FABP3CA1 | |
| Acetic Acid SCHEMBL5914494 | 0.77 | GPR84 (0.40) | FABP3GPR84MEN1KMT2A | |
| Octane SCHEMBL28390058 | 0.77 | CES2 (0.60) | CA2CES2CES1CA1GPR84 | |
| Acetic Acid SCHEMBL10922905 | 0.77 | GPR84 (0.40) | FABP3GPR84MEN1KMT2A | |
| Acetic Acid SCHEMBL14938024 | 0.76 | CES2 (0.47) | CES2CES1FABP3GPR84MEN1 | |
| Acetic Acid SCHEMBL1782736 | 0.76 | GPR84 (0.39) | FABP3GPR84MEN1KMT2A | |
| SCHEMBL14829251 | 0.74 | CA1 (0.42) | CA2CES2CES1FABP3CA1 | |
| SCHEMBL9182831 | 0.74 | CA1 (0.42) | CA2CES2CES1FABP3CA1 | |
| SCHEMBL5186150 | 0.74 | AKR1B1 (0.41) | FABP3GPR84MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119871232-A | Complex micro-fine inner runner fluid polishing method based on weak oxidation and micro-friction composite effect | 南京尚吉增材制造研究院有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-115181455-A | Novel pigment based on temperature discoloration and preparation method thereof | 深圳市添金利新材料科技有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-107611396-B | Sulfur-asphalt-based/graphene composite material and preparation method and application thereof | 中国科学院山西煤炭化学研究所 | 2019-12-24 | — | — | CN | claimed |
| CN-119871232-A | Complex micro-fine inner runner fluid polishing method based on weak oxidation and micro-friction composite effect | 南京尚吉增材制造研究院有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-20240099955-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | HTL BIOTECHNOLOGY INNOVATION INC. | 2024-03-28 | — | — | US | disclosed |
| EP-4288084-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | Modern Meadow, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-115645347-A | Fermented anti-hair loss shampoo and preparation method thereof | 北京九州益华化妆品有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2022170114-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | MODERN MEADOW, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-109498513-B | Natural tricholoma matsutake extract and application thereof in mild shampoo | 广州艾儿化妆品有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-109431916-B | Mild baby shampoo and preparation method thereof | 广东汉粹生物药业有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-109023321-B | Organic chemical silver plating liquid medicine | 厦门银方新材料科技有限公司 | 2020-11-13 | — | — | CN | disclosed |
| US-20190008747-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2019-01-10 | — | — | US | disclosed |
| EP-3398585-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-10111822-B2 | External dermal composition for anti-ageing and method for producing the same | Hayashibara Co., Ltd. (JP) | 2018-10-30 | — | — | US | disclosed |
| EP-2939657-B1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | HAYASHIBARA CO (JP) | 2018-08-08 | — | — | EP | disclosed |
| CN-105997549-A | Composition for skin cleaning | 株式会社芳珂 | 2016-10-12 | — | — | CN | disclosed |
| CN-105997550-A | Powdery or granular skin cleansing composition | 株式会社芳珂 | 2016-10-12 | — | — | CN | disclosed |
| US-20150342854-A1 | EXTERNAL DERMAL COMPOSITION FOR ANTI-AGEING AND METHOD FOR PRODUCING THE SAME | Hayashibara Co., Ltd. (JP) | 2015-12-03 | — | — | US | disclosed |
| EP-2939657-A1 | SKIN-EXTERIOR ANTI-AGEING COMPOSITION AND PRODUCTION METHOD THEREFOR | Hayashibara Co., Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| EP-0070191-A1 | Detergent additives and detergent compositions containing them | UNILEVER PLC (GB) | 1983-01-19 | — | — | EP | disclosed |