Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394890 | 0.88 | DHODH (0.50) | ALDH1A1GAADHODHPDE10AKDM4E | |
| Hydrochloric Acid SCHEMBL11375365 | 0.86 | DHODH (0.49) | ALDH1A1GAADHODHPDE10AKDM4E | |
| SCHEMBL11375363 | 0.86 | GAA (0.46) | ALDH1A1GAADHODHPDE10AKDM4E | |
| SCHEMBL6669896 | 0.85 | DHODH (0.41) | GRM2DHODHPDE10AELANE | |
| SCHEMBL14471222 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAADHODHPDE10AKDM4E | |
| SCHEMBL8124347 | 0.80 | GRM2 (0.48) | GRM2DHODHPDE10A | |
| SCHEMBL30713425 | 0.79 | DHODH (0.46) | GRM2DHODHPDE10AKDM4EPOLB | |
| SCHEMBL399026 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1GAAKDM4EMAPTNPC1 | |
| SCHEMBL12693813 | 0.77 | ERN1 (0.53) | ALDH1A1GAAKDM4EMAPTBACE1 | |
| SCHEMBL3226084 | 0.76 | DHODH (0.44) | GRM2DHODHPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012639-B1 | QUINOLEIN-3-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE IN MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1983-09-07 | — | — | EP | disclosed |