Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201745 | 0.85 | GRM2 (0.42) | DHODHPDE10AGRM2ELANE | |
| SCHEMBL30713425 | 0.79 | DHODH (0.46) | DHODHPDE10ATP53HSD17B10ERN1 | |
| SCHEMBL8124347 | 0.76 | GRM2 (0.48) | DHODHPDE10ATP53HSD17B10ERN1 | |
| SCHEMBL3226084 | 0.76 | DHODH (0.44) | DHODHPDE10ATP53HSD17B10ERN1 | |
| SCHEMBL61597 | 0.73 | HSD17B10 (0.52) | DHODHPDE10ATP53HSD17B10GRM2 | |
| SCHEMBL30148539 | 0.73 | HSD17B10 (0.52) | DHODHPDE10ATP53HSD17B10GRM2 | |
| SCHEMBL394890 | 0.72 | DHODH (0.50) | DHODHPDE10AHSD17B10ELANEMEN1 | |
| Hydrochloric Acid SCHEMBL11375365 | 0.71 | DHODH (0.49) | DHODHPDE10AHSD17B10ELANEMEN1 | |
| SCHEMBL11375363 | 0.71 | GAA (0.46) | DHODHPDE10AERN1ELANEMEN1 | |
| SCHEMBL1332157 | 0.70 | MAP2K3 (0.50) | DHODHPDE10AHSD17B10GRM2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |