Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579524 | 0.76 | KDM4E (0.33) | PDE3BPDE3AALDH1A1TYMP | |
| SCHEMBL8441474 | 0.76 | PDE3B (0.42) | PDE3BPDE3AALDH1A1TYMP | |
| SCHEMBL29004227 | 0.67 | TSHR (0.35) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL10885262 | 0.64 | GPR84 (0.42) | HIF1ATYMP | |
| SCHEMBL16063098 | 0.63 | — | — | |
| SCHEMBL10885266 | 0.63 | GPR84 (0.44) | TYMP | |
| SCHEMBL5253771 | 0.61 | TAAR1 (0.46) | TSHRHIF1ATRPV1ALDH1A1 | |
| Glutaral SCHEMBL8000996 | 0.60 | HIF1A (0.77) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL22766845 | 0.59 | PDE3B (0.46) | PDE3BPDE3AALDH1A1TYMP | |
| SCHEMBL20799748 | 0.58 | TYMP (0.50) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079049-A2 | Novel substituted alkanoylimidazol-2-one derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | disclosed |