Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 9/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 3/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11874577 | 0.81 | SOAT1 (0.53) | TSHRSOAT2SOAT1ALDH1A1LMNA | |
| SCHEMBL11200731 | 0.81 | SOAT1 (0.53) | TSHRSOAT2SOAT1ALDH1A1LMNA | |
| SCHEMBL8942096 | 0.78 | TSHR (0.49) | ALKBH5TSHRCTSAALDH1A1MAPT | |
| SCHEMBL10638765 | 0.75 | MAPT (0.56) | CDC25BPTPN2PTPN1PTPN11ALDH1A1 | |
| SCHEMBL28960890 | 0.75 | MAPT (0.56) | CDC25BPTPN2PTPN1PTPN11ALDH1A1 | |
| SCHEMBL11357268 | 0.75 | MAPT (0.56) | CDC25BPTPN2PTPN1PTPN11ALDH1A1 | |
| SCHEMBL10641781 | 0.75 | MAPT (0.56) | CDC25BPTPN2PTPN1PTPN11ALDH1A1 | |
| SCHEMBL11441556 | 0.75 | ALKBH5 (0.59) | ALKBH5TSHRCTSAALDH1A1MAPT | |
| SCHEMBL951472 | 0.75 | ALKBH5 (0.73) | ALKBH5TSHRCTSAALDH1A1MAPT | |
| SCHEMBL10885655 | 0.75 | ALKBH5 (0.50) | ALKBH5TSHRCTSAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387159-A | Light sensitive, color photographic silver halide compositions with DIR-couplers | VEB FILMFABRIK WOLFEN (DD) | 1983-06-07 | — | — | US | disclosed |
| US-4286054-A | DYESTUFFS, DEVELOPMENT INHIBITOR RELEASING | VEB FILMFABRIK WOLFEN (DD) | 1981-08-25 | — | — | US | disclosed |