SCHEMBL951472

SCHEMBL951472

O=C(O)c1cc(=O)n(-c2ccccc2)[nH]1

nearest known ligand 0.73

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 15/20 0.73
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
BLM P54132 1/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TSHR P16473 1/20 0.51
CTSA P10619 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11334785 0.87 ALKBH5 (0.61) ALKBH5ALDH1A1LMNAPOLBMAPT
SCHEMBL11441556 0.86 ALKBH5 (0.59) ALKBH5ALDH1A1LMNAPOLBMAPT
SCHEMBL6143137 0.86 ALKBH5 (0.55) ALKBH5ALDH1A1LMNAPOLBMAPT
SCHEMBL10976136 0.86 ALKBH5 (0.55) ALKBH5ALDH1A1LMNAPOLBMAPT
SCHEMBL11300860 0.85 ALKBH5 (0.72) ALKBH5ALDH1A1MAPTCTSA
SCHEMBL11043171 0.84 ALKBH5 (0.55) ALKBH5ALDH1A1LMNAPOLBMAPT
SCHEMBL1265504 0.84 ALKBH5 (0.67) ALKBH5ALDH1A1MAPT
SCHEMBL9505312 0.84 ALKBH5 (1.00) ALKBH5ALDH1A1MAPT
SCHEMBL10787351 0.84 ALKBH5 (0.71) ALKBH5ALDH1A1MAPT
SCHEMBL11774629 0.84 ALKBH5 (0.71) ALKBH5ALDH1A1MAPTCTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574542-A Environment-friendly plastic film and preparation method thereof 窦怀辉 2021-03-30 CN claimed
CN-109181483-B Extinction curing agent for epoxy resin powder coating and preparation method and application thereof 安徽泰达新材料股份有限公司 2021-02-09 CN claimed
CN-105940537-B Graphene composite, preparation method of graphene composite and electrode for lithium ion battery containing graphene composite 东丽先端材料研究开发(中国)有限公司 2020-12-08 CN claimed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 EP claimed
CN-104852051-A Graphene powder and preparation method and lithium ion battery containing graphene powder TORAY ADVANCED MATERIALS RES LAB CHINA CO LTD 2015-08-19 CN claimed
US-7988740-B2 Keratin dyeing compositions comprising a radical scavenger and use thereof THE PROCTER & GAMBLE COMPANY (US) 2011-08-02 US claimed
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof NOXELL CORPORATION 2011-02-17 US claimed
EP-0333653-B1 Reactive dyes, process for their preparation and their use CIBA GEIGY AG (CH) 1994-06-08 EP claimed
US-4963659-A DYEING CELLULOSE, PRINTING TEXTILES CIBA-GEIGY CORPORATION (US) 1990-10-16 US claimed
US-4496727-A ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS CIBA-GEIGY CORPORATION (US) 1985-01-29 US claimed
US-4486237-A INORGANIC AND ORGANIC MONTEFLUOUS S.P.A. (IT) 1984-12-04 US claimed
EP-0043927-B1 PROCESS FOR PREPARING REACTIVE AZO DYESTUFFS BAYER AG (DE) 1984-05-16 EP claimed
EP-0043927-A2 Process for preparing reactive azo dyestuffs BAYER AG (DE) 1982-01-20 EP claimed
US-3976488-A COUPLER, EXTENDER, DISPERSION MEDIUM MITA INDUSTRIAL COMPANY, LTD. (JA) 1976-08-24 US claimed
JP-7126560-A None JP disclosed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US disclosed
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 EP disclosed
US-3948661-A Process for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LTD. (JA) 1976-04-06 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110035885-A1 Keratin Dyeing Compositions Comprising a Radical Scavenger and Use Thereof KRT18, LPO, CYB5R3 ALKBH5 413/4885ALDH1A1 326/4885LMNA 433/4885
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 ALKBH5 1080/4885ALDH1A1 2333/4885LMNA 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.