Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CTSA | P10619 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757089 | 0.95 | TSHR (0.51) | TSHRTDP1L3MBTL1MEN1GAA | |
| SCHEMBL10627912 | 0.95 | TSHR (0.51) | TSHRTDP1L3MBTL1MEN1GAA | |
| SCHEMBL10885655 | 0.92 | ALKBH5 (0.50) | TSHRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL11516674 | 0.89 | ALDH1A1 (0.48) | TSHRTDP1L3MBTL1MEN1GAA | |
| SCHEMBL2229684 | 0.87 | MAPT (0.62) | TSHRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL1819463 | 0.81 | ALKBH5 (0.61) | TSHRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL11043171 | 0.79 | ALKBH5 (0.55) | TSHRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL11201758 | 0.78 | ALKBH5 (0.48) | TSHRL3MBTL1MEN1GAAMAPT | |
| SCHEMBL5527198 | 0.76 | ALDH1A1 (0.60) | TSHRTDP1MEN1GAAMAPT | |
| SCHEMBL9196875 | 0.75 | ALDH1A1 (0.62) | TDP1MEN1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |