Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199334 | 0.95 | CNR2 (0.34) | CNR2CNR1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL11201366 | 0.75 | HTR2C (0.33) | CNR2CNR1TSHRMAP4K4MAPK9 | |
| SCHEMBL11202778 | 0.70 | CNR2 (0.33) | CNR2CNR1TSHRHDAC8HDAC6 | |
| SCHEMBL15118488 | 0.69 | PKM (0.43) | CNR2CNR1TSHRHDAC8HDAC6 | |
| SCHEMBL10852053 | 0.67 | TRIM24 (0.47) | CNR2CNR1TSHRALDH1A1 | |
| SCHEMBL20945145 | 0.66 | PARP1 (0.44) | CNR2CNR1TSHRHDAC8HDAC6 | |
| SCHEMBL6536824 | 0.65 | PSMB1 (0.47) | TSHRALDH1A1TP53 | |
| SCHEMBL27963898 | 0.64 | CNR2 (0.36) | CNR2CNR1TSHRMAPTALDH1A1 | |
| SCHEMBL11198523 | 0.64 | MAP4K4 (0.33) | TSHRMAP4K4MAPK9CSNK1A1CSNK1D | |
| SCHEMBL6297486 | 0.63 | CNR2 (0.43) | CNR2CNR1TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |