Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | FRK | P42685 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.30 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202778 | 0.95 | CNR2 (0.33) | HTR2CHTR2AHTR2BHSD11B1ALDH1A1 | |
| SCHEMBL11344641 | 0.89 | HTR2C (0.35) | HTR2CHTR2AHTR2BHSD11B1ALDH1A1 | |
| SCHEMBL386002 | 0.76 | ALDH1A1 (0.37) | HTR2CHTR2AHTR2BALDH1A1TSHR | |
| SCHEMBL11201768 | 0.75 | CNR2 (0.33) | ALDH1A1TSHRCNR1CNR2PRKD3 | |
| SCHEMBL11198523 | 0.72 | MAP4K4 (0.33) | TSHRPRKD3MAP4K4FRKMAPK9 | |
| SCHEMBL385866 | 0.71 | HSD11B1 (0.46) | HTR2CHTR2AHTR2BHSD11B1ALDH1A1 | |
| SCHEMBL19556667 | 0.71 | TBXAS1 (0.35) | ALDH1A1TSHRCNR1CNR2 | |
| SCHEMBL7675436 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL27372583 | 0.70 | CYP11B1 (0.36) | ALDH1A1CNR2 | |
| SCHEMBL11199334 | 0.70 | CNR2 (0.34) | ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410534-A | 3-Substituted-5,6,7,8-tetrahydropyrrolo[1,2-a]-pyridine-and 6,7,8,9-tetrahydro-5H-pyrrolo[1,2-a]-azepine carboxylic acid derivatives useful as blood platelet aggregation inhibitors | SYNTEX (U.S.A.) INC. (US) | 1983-10-18 | — | — | US | disclosed |