Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260427 | 0.82 | ALDH1A1 (0.43) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL4084320 | 0.80 | TDP2 (0.38) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL9788461 | 0.73 | KAT8 (0.55) | MAPTALDH1A1HTTPKMKAT8 | |
| SCHEMBL31222678 | 0.73 | MAPT (0.75) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL9296161 | 0.73 | KAT8 (0.55) | MAPTALDH1A1HTTPKMKAT8 | |
| SCHEMBL2223232 | 0.73 | MAPT (0.66) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL15196197 | 0.71 | KAT8 (0.40) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL11504172 | 0.71 | KAT8 (0.42) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL23064868 | 0.69 | KAT8 (0.50) | MAPTALDH1A1LMNAGAAHTT | |
| SCHEMBL14378351 | 0.69 | TDP2 (0.38) | MAPTALDH1A1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019219-B1 | IMPROVED PHOTOIMAGING SYSTEMS WITH CYCLIC HYDRAZIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-22 | — | — | EP | disclosed |