Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200638 | 0.95 | DRD2 (0.69) | DRD2MEN1KMT2AHTR2ADRD3 | |
| Ethylene SCHEMBL11194476 | 0.93 | DRD2 (0.67) | DRD2MEN1KMT2AHTR2ADRD3 | |
| SCHEMBL20652674 | 0.79 | DRD2 (1.00) | DRD2MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL4512783 | 0.77 | DRD2 (0.71) | DRD2MEN1KMT2AHTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL7303580 | 0.76 | DRD2 (0.69) | DRD2MEN1KMT2AHTR2ADRD3 | |
| SCHEMBL8183381 | 0.74 | DRD3 (0.65) | DRD2MEN1KMT2AHTR2ADRD3 | |
| SCHEMBL9051860 | 0.74 | DRD2 (0.67) | DRD2MEN1KMT2AHTR2ADRD3 | |
| SCHEMBL6348978 | 0.74 | ALDH1A1 (0.57) | DRD2MEN1KMT2ADRD3CHRM2 | |
| SCHEMBL11834324 | 0.74 | TSHR (0.67) | DRD2MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL11834858 | 0.74 | TSHR (0.67) | DRD2MEN1KMT2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414219-A | ANTICONVULSANTS, TRANQUILIZERS, ANALGESTICS | AMERICAN HOECHST CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4311703-A | PYRROLIDINE AND PIPERIDINE DERIVATIVES | AMERICAN HOECHST CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4241071-A | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes | AMERICAN HOECHST CORPORATION (US) | 1980-12-23 | — | — | US | disclosed |