Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 4/20 | 0.66 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | DRD3 | P35462 | 3/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11829536 | 0.99 | TSHR (0.70) | TSHRDRD2HTR1ADRD3DRD4 | |
| SCHEMBL11834324 | 0.90 | TSHR (0.67) | TSHRDRD2HTR1ADRD3DRD4 | |
| SCHEMBL9051860 | 0.85 | DRD2 (0.67) | DRD2HTR1ADRD3HTR2AKDM4E | |
| SCHEMBL6234537 | 0.84 | DRD2 (0.77) | TSHRDRD2HTR1ADRD3DRD4 | |
| SCHEMBL11828414 | 0.84 | TSHR (0.64) | TSHRDRD2HTR1ADRD3HTR2A | |
| SCHEMBL9050871 | 0.84 | DRD2 (0.67) | TSHRDRD2HTR1ADRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11553970 | 0.84 | DRD2 (0.67) | TSHRDRD2HTR7SIGMAR1 | |
| SCHEMBL4512783 | 0.83 | DRD2 (0.71) | DRD2HTR1ADRD3HTR2AMEN1 | |
| SCHEMBL16986166 | 0.82 | TSHR (0.97) | TSHRDRD2HTR1ADRD3DRD4 | |
| SCHEMBL9052603 | 0.82 | DRD2 (0.71) | TSHRDRD2HTR1ADRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |