Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204170 | 0.89 | NPC1 (0.49) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11196455 | 0.86 | TDP1 (0.49) | USP2HTTMEN1KMT2ATSHR | |
| SCHEMBL11200538 | 0.86 | SMN1; SMN2 (0.57) | USP2HTTMEN1KMT2ATSHR | |
| SCHEMBL11196667 | 0.81 | USP2 (0.50) | USP2HTTMEN1KMT2ATSHR | |
| SCHEMBL11200409 | 0.81 | SMN1; SMN2 (0.49) | USP2HTTMEN1KMT2ATSHR | |
| SCHEMBL11193548 | 0.80 | LMNA (0.47) | HTTSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL11200546 | 0.79 | SMN1; SMN2 (0.52) | USP2HTTMEN1KMT2ATSHR | |
| SCHEMBL11196859 | 0.79 | LMNA (0.49) | USP2HTTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11193818 | 0.78 | USP2 (0.47) | USP2HTTMEN1KMT2ACYP3A4 | |
| SCHEMBL11198251 | 0.76 | TDP1 (0.62) | HTTMEN1KMT2ATSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |