Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202153 | 1.00 | LMNA (0.40) | LMNAMAPTNPC1RAB9ACASP3 | |
| SCHEMBL11199256 | 0.86 | GPR52 (0.42) | RELASMN1; SMN2 | |
| SCHEMBL11199259 | 0.86 | GPR52 (0.42) | RELASMN1; SMN2 | |
| SCHEMBL10481511 | 0.86 | NPSR1 (0.51) | LMNAMAPTNPC1RAB9ACASP3 | |
| SCHEMBL10518172 | 0.82 | MEN1 (0.47) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL10518177 | 0.82 | MEN1 (0.47) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL10518184 | 0.82 | MEN1 (0.47) | LMNAMAPTNPC1RAB9ARECQL | |
| SCHEMBL3750871 | 0.79 | ACE (0.44) | LMNAACERECQLPREPALDH1A1 | |
| SCHEMBL10340335 | 0.79 | ACE (0.44) | LMNAACERECQLPREPALDH1A1 | |
| SCHEMBL10481515 | 0.76 | ALDH1A1 (0.52) | ACEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374249-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-02-15 | — | — | US | disclosed |