Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 6/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200284 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL11195367 | 0.86 | CASR (0.57) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL11195201 | 0.85 | EPHX2 (0.55) | ALDH1A1SMN1; SMN2CASRFADS1NPC1 | |
| SCHEMBL11200148 | 0.82 | NPC1 (0.52) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL11200409 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1LMNASMN1; SMN2HTTMTNR1A | |
| SCHEMBL11195455 | 0.79 | EPHX2 (0.63) | ALDH1A1LMNASMN1; SMN2HTTNPC1 | |
| SCHEMBL11203072 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL11200327 | 0.79 | CNR1 (0.50) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL11200290 | 0.78 | CNR1 (0.44) | ALDH1A1LMNASMN1; SMN2HTTNCOA1 | |
| SCHEMBL11196501 | 0.78 | MTNR1A (0.52) | ALDH1A1LMNASMN1; SMN2CASRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |