Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389308 | 0.82 | KMT2A (0.51) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL126697 | 0.81 | ALDH1A1 (0.59) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL27372795 | 0.80 | KMT2A (0.70) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11059936 | 0.78 | GAA (0.72) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL2521071 | 0.78 | TSHR (0.53) | NPC1RAB9AMEN1KMT2ACES2 | |
| SCHEMBL4929277 | 0.78 | MEN1 (0.77) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL29251267 | 0.78 | KMT2A (0.52) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL6457145 | 0.77 | MAPT (0.73) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL27894878 | 0.77 | MAPT (0.55) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL27800573 | 0.77 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091851-A1 | Process for preparing aryl ethers carrying different substituents on the two aromatic nuclei | Institut Français du Pétrole (FR) | 1983-10-19 | — | — | EP | disclosed |