SCHEMBL126697

SCHEMBL126697

O=C(NOc1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
POLB P06746 1/20 0.59
NPC1 O15118 7/20 0.53
RAB9A P51151 7/20 0.53
HDAC8 Q9BY41 2/20 0.52
HDAC3 O15379 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC2 Q92769 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
IDO1 P14902 1/20 0.52
ALOX15 P16050 1/20 0.52
CA9 Q16790 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
PGR P06401 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29251267 0.88 KMT2A (0.52) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL27800573 0.87 NPC1 (0.56) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL27634795 0.87 JAK2 (0.56) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL8893985 0.85 MAPK13 (0.55) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL13605110 0.84 RAB9A (0.58) ALDH1A1MAPTPOLBNPC1RAB9A
SCHEMBL28358263 0.84 HDAC8 (0.53) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL28887476 0.84 KMT2A (0.47) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL13612965 0.82 PLK1 (0.54) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL9402689 0.82 RAB9A (0.43) ALDH1A1MAPTKMT2APOLBNPC1
SCHEMBL4801662 0.82 ALDH1A1 (0.42) ALDH1A1MAPTKMT2APOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546106-A Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof 宁夏大学 2024-08-27 CN claimed
CN-117164517-A Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof 西北农林科技大学 2023-12-05 CN claimed
CN-112292035-A Water-dispersible pesticide composition 日本化药株式会社 2021-01-29 CN claimed
CN-1491106-A Method for treating oesophageal motility disorders and gastro-oesophageal reflux disease �޲��ء��߶�ķ˹�� 2004-04-21 CN claimed
CN-117164517-B Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof 西北农林科技大学 2026-02-10 CN disclosed
CN-118546106-A Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof 宁夏大学 2024-08-27 CN disclosed
CN-118546106-A Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof 宁夏大学 2024-08-27 CN disclosed
CN-118546106-A Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof 宁夏大学 2024-08-27 CN disclosed
CN-117164517-A Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof 西北农林科技大学 2023-12-05 CN disclosed
CN-117164517-A Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof 西北农林科技大学 2023-12-05 CN disclosed
US-11382884-B2 Method for reducing lung infection Respirion Pharmaceuticals Pty Ltd (CA) 2022-07-12 US disclosed
CN-112292035-A Water-dispersible pesticide composition 日本化药株式会社 2021-01-29 CN disclosed
WO-2001076593-A2 BILE SECRETION PROMOTING COMPOSITION A 15-KETO PROSTAGLANDIN SUCAMPO AG (CH) 2001-10-18 WO disclosed
WO-2001070233-A2 APOPTOSIS INHIBITING COMPOSITION COMPRISING A 15-KETO-PROSTAGLANDIN OR DERIVATIVE THEREOF SUCAMPO AG (CH) 2001-09-27 WO disclosed
WO-2001068072-A2 COMPOSITION FOR USE IN TREATMENT OF OCULAR HYPERTENSION AND GLAUCOMA SUCAMPO AG (CH) 2001-09-20 WO disclosed
WO-2001027099-A2 BICYCLIC COMPOUNDS COMPOSITION AND METHOD FOR STABILIZING THE SAME SUCAMPO, A.G. (CH) 2001-04-19 WO disclosed
WO-2001005388-A2 USE OF A FATTY DERIVATIVE FOR THE TREATMENT OF EXTERNAL SECRETIONDISORDERS SUCAMPO, A.G. (CH) 2001-01-25 WO disclosed
US-5024691-A Substituted phenoxy benzamide herbicides and methods of use ICI AMERICAS INC. (US) 1991-06-18 US disclosed
US-4009116-A Process of preparing substantially organic waste liquids containing radioactive or toxic substances for safe, non-pollutive handling, transportation and permanent storage BAYER AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed
US-3960762-A Production of absorbents BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed