SCHEMBL11203608

SCHEMBL11203608

COC(CCl)Oc1ccccc1OC(=O)N(C)[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
ACHE P22303 1/20 0.37
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
HSD17B10 Q99714 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
NCEH1 Q6PIU2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408436 0.79 ALDH1A1 (0.61) ALDH1A1ACHEMTNR1AMTNR1BKDM4E
SCHEMBL73994 0.79 ALDH1A1 (0.61) ALDH1A1ACHEMTNR1AMTNR1BKDM4E
SCHEMBL11272508 0.74 MEN1 (0.35) ALDH1A1KDM4ETSHRKMT2ANPC1
SCHEMBL10657484 0.72 TSPO (0.41) ALDH1A1KDM4EKMT2ANPC1RAB9A
SCHEMBL11142667 0.70 TP53 (0.48) ALDH1A1ACHEKDM4ETSHRKMT2A
SCHEMBL9857296 0.68 POLB (0.48) ALDH1A1TSHRKMT2ALMNANPC1
SCHEMBL11784197 0.68 ALDH1A1 (0.58) ALDH1A1ACHEMTNR1AMTNR1BKDM4E
SCHEMBL11788905 0.65 ALDH1A1 (0.61) ALDH1A1ACHEMTNR1AMTNR1BKDM4E
SCHEMBL11789118 0.65 ALDH1A1 (0.61) ALDH1A1ACHEMTNR1AMTNR1BKDM4E
SCHEMBL10574854 0.64 ALDH1A1 (0.65) ALDH1A1ACHEKDM4ETSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0033098-B1 N-METHYL-N-SILYL-CARBAMATES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1983-11-23 EP claimed
US-4360517-A INSECTICIDES, MITICIDES, AND NEMATOCIDES BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US claimed
EP-0033098-A2 N-methyl-N-silyl-carbamates, processes for their preparation and their use as pesticides BASF Aktiengesellschaft (DE) 1981-08-05 EP claimed
EP-0033098-B1 N-METHYL-N-SILYL-CARBAMATES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1983-11-23 EP disclosed
US-4360517-A INSECTICIDES, MITICIDES, AND NEMATOCIDES BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
EP-0033098-A2 N-methyl-N-silyl-carbamates, processes for their preparation and their use as pesticides BASF Aktiengesellschaft (DE) 1981-08-05 EP disclosed