Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208744 | 0.84 | KDM4E (0.38) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11202466 | 0.84 | HTR6 (0.46) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11200734 | 0.82 | HTR3A (0.41) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11202798 | 0.82 | HTR6 (0.37) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11197283 | 0.81 | SMN1; SMN2 (0.46) | KDM4EALDH1A1MAPTHRH4ADRA1D | |
| SCHEMBL11206086 | 0.81 | HCRTR1 (0.51) | HCRTR1HCRTR2ADRA1DADRA1AADRA1B | |
| SCHEMBL11206717 | 0.80 | KDM4E (0.38) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11197408 | 0.80 | KDM4E (0.52) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| SCHEMBL11205332 | 0.80 | KDM4E (0.39) | HCRTR1HCRTR2KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11206153 | 0.79 | KDM4E (0.51) | HCRTR1HCRTR2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |