Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205332 | 0.87 | KDM4E (0.39) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11200654 | 0.85 | HTR6 (0.42) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11204268 | 0.84 | HRH4 (0.44) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11206200 | 0.83 | HTR3A (0.38) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11204008 | 0.82 | HCRTR1 (0.49) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11203060 | 0.81 | KDM4E (0.37) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11202691 | 0.81 | KHK (0.42) | HTR3AKDM4EALDH1A1MAPTHRH4 | |
| Hydrochloric Acid SCHEMBL11201994 | 0.80 | KHK (0.41) | HTR3AKDM4EALDH1A1MAPTHRH4 | |
| SCHEMBL11205447 | 0.78 | HRH4 (0.38) | HTR3AMAPK1KDM4EALDH1A1MAPT | |
| SCHEMBL11198545 | 0.76 | HRH4 (0.42) | HTR3AMAPK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |