Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208747 | 0.87 | TYR (0.42) | TYRADRA2AADRA2BADRA1ACYP2D6 | |
| SCHEMBL29358402 | 0.87 | ADRA2A (0.47) | TYRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL115911 | 0.87 | ADRA2A (0.47) | TYRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL5605956 | 0.83 | ADRA2A (0.45) | TYRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL4156669 | 0.80 | TYR (0.48) | TYRADRA2AADRA2CCYP2D6CYP3A4 | |
| SCHEMBL29638766 | 0.78 | ACP3 (0.50) | TYRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL28666265 | 0.78 | ACP3 (0.50) | TYRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL710709 | 0.78 | ACP3 (0.50) | TYRADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11203841 | 0.77 | P2RX7 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL2844549 | 0.76 | TYR (0.42) | TYRADRA2AADRA2BADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |