Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11199939 | 0.99 | OPRL1 (0.54) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL11206162 | 0.84 | OPRL1 (0.65) | OPRL1POLBSIGMAR1CCR3KDM4E | |
| Hydrochloric Acid SCHEMBL11199734 | 0.83 | OPRL1 (0.64) | OPRL1POLBSIGMAR1CCR3KDM4E | |
| SCHEMBL11195174 | 0.79 | OPRL1 (0.77) | OPRL1OPRM1POLBSIGMAR1CCR3 | |
| SCHEMBL11840691 | 0.78 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL11193563 | 0.78 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1POLB | |
| Hydrochloric Acid SCHEMBL11193622 | 0.78 | OPRL1 (0.75) | OPRL1OPRM1POLBSIGMAR1CCR3 | |
| SCHEMBL11195132 | 0.76 | ALDH1A1 (0.44) | OPRL1OPRD1KDM4EKMT2A | |
| SCHEMBL11206538 | 0.75 | OPRL1 (0.47) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL3119581 | 0.74 | OPRM1 (0.45) | OPRL1OPRM1OPRK1OPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414219-A | ANTICONVULSANTS, TRANQUILIZERS, ANALGESTICS | AMERICAN HOECHST CORPORATION (US) | 1983-11-08 | — | — | US | claimed |
| US-4414219-A | ANTICONVULSANTS, TRANQUILIZERS, ANALGESTICS | AMERICAN HOECHST CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4311703-A | PYRROLIDINE AND PIPERIDINE DERIVATIVES | AMERICAN HOECHST CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4241071-A | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes | AMERICAN HOECHST CORPORATION (US) | 1980-12-23 | — | — | US | disclosed |