Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11199734 | 0.99 | OPRL1 (0.64) | OPRL1POLBKDM4EKMT2ACCR3 | |
| SCHEMBL11195174 | 0.92 | OPRL1 (0.77) | OPRL1POLBKDM4EKMT2ACCR3 | |
| Hydrochloric Acid SCHEMBL11193622 | 0.90 | OPRL1 (0.75) | OPRL1POLBKDM4EKMT2ACCR3 | |
| SCHEMBL350525 | 0.89 | OPRL1 (0.65) | OPRL1POLBKDM4EKMT2ACCR3 | |
| SCHEMBL6860104 | 0.85 | SIGMAR1 (0.54) | OPRL1POLBKDM4EKMT2ASIGMAR1 | |
| SCHEMBL11204348 | 0.84 | OPRL1 (0.55) | OPRL1POLBKDM4EKMT2ACCR3 | |
| SCHEMBL11202280 | 0.84 | OPRL1 (0.56) | OPRL1POLBKDM4EKMT2ACCR3 | |
| Hydrochloric Acid SCHEMBL11199939 | 0.83 | OPRL1 (0.54) | OPRL1POLBKDM4EKMT2ACCR3 | |
| Bromide SCHEMBL11203082 | 0.83 | OPRL1 (0.55) | OPRL1POLBKDM4EKMT2ACCR3 | |
| SCHEMBL10226080 | 0.82 | OPRL1 (0.81) | OPRL1POLBKDM4EKMT2ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414219-A | ANTICONVULSANTS, TRANQUILIZERS, ANALGESTICS | AMERICAN HOECHST CORPORATION (US) | 1983-11-08 | — | — | US | claimed |