Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035469 | 0.84 | MAPT (0.52) | MAPTLMNASMN1; SMN2RAB9ATP53 | |
| SCHEMBL9688656 | 0.82 | MAPT (0.68) | MAPTFAAHLMNASMN1; SMN2RAB9A | |
| SCHEMBL692169 | 0.82 | MAPT (0.47) | MAPTLMNASMN1; SMN2RAB9ATP53 | |
| SCHEMBL6995111 | 0.80 | SMN1; SMN2 (0.59) | MAPTLMNASMN1; SMN2RAB9ATP53 | |
| SCHEMBL17844527 | 0.78 | MAPT (0.44) | MAPTLMNATP53KDM4EALDH1A1 | |
| SCHEMBL31560851 | 0.78 | MAPT (0.48) | MAPTLMNASMN1; SMN2RAB9ATP53 | |
| Bromide SCHEMBL10923172 | 0.77 | MAPT (0.46) | MAPTFAAHLMNASMN1; SMN2RAB9A | |
| SCHEMBL18470230 | 0.76 | MTNR1A (0.47) | MAPTLMNASMN1; SMN2RAB9ATP53 | |
| SCHEMBL14564360 | 0.76 | MAPT (0.56) | MAPTLMNASMN1; SMN2RAB9ATHRB | |
| SCHEMBL32670475 | 0.75 | MAPT (0.43) | MAPTLMNASMN1; SMN2RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |