Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL11211940 | 0.92 | MAPT (0.63) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL75124 | 0.92 | MAPT (0.62) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| Benzyl Alcohol SCHEMBL11208104 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL4907408 | 0.84 | LMNA (0.55) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL10242664 | 0.81 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL5697386 | 0.80 | MAPT (0.53) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL14564409 | 0.80 | MAPT (0.78) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL10916558 | 0.79 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL13337957 | 0.78 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL23119878 | 0.78 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101263128-B | Sulfonation method of 1, 2-benzisoxazole-3-acetic acid | DAINIPPON SUMITOMO PHARMA CO | 2011-02-16 | — | — | CN | disclosed |
| CN-101263128-A | Sulfonation method of 1, 2-benzisoxazole-3-acetic acid | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-09-10 | — | — | CN | disclosed |
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |