Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75124 | 0.91 | MAPT (0.62) | LMNACA12CA1CA2CA3 | |
| Methyl Alcohol SCHEMBL11211940 | 0.88 | MAPT (0.63) | LMNACA12CA1CA2CA3 | |
| Toluene SCHEMBL11204804 | 0.84 | MAPT (0.67) | LMNACA12CA1CA2CA3 | |
| Benzyl Alcohol SCHEMBL11208104 | 0.82 | MAPT (0.54) | LMNACA12CA1CA2CA3 | |
| SCHEMBL5697386 | 0.79 | MAPT (0.53) | LMNACA12CA1CA2CA3 | |
| SCHEMBL10916558 | 0.78 | SMN1; SMN2 (0.57) | LMNACA12CA1CA2CA3 | |
| SCHEMBL10643067 | 0.78 | ALDH1A1 (0.57) | LMNACA12CA1CA2CA3 | |
| SCHEMBL10242664 | 0.76 | SMN1; SMN2 (0.59) | LMNACA12CA1CA2CA3 | |
| SCHEMBL3143718 | 0.76 | LMNA (0.73) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2793131 | 0.76 | LMNA (0.58) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375233-B2 | Process for the preparation of zonisamide and the intermediates thereof | APOTEX PHARMACHEM INC. (CA) | 2008-05-20 | — | — | US | disclosed |
| US-20080033181-A1 | Process for the preparation of Zonisamide and the intermediates thereof | APOTEX PHARMACHEM INC. | 2008-02-07 | — | — | US | disclosed |
| US-20070142644-A1 | Process for the preparation of zonisamide and the intermediates thereof | APOTEX PHARMACHEM INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033181-A1 | Process for the preparation of Zonisamide and the intermediates thereof | CYP2F1, CYP4F2, CA3 | LMNA 2871/4885CA12 60/4885CA1 9/4885 |
| US-20070142644-A1 | Process for the preparation of zonisamide and the intermediates thereof | CYP2F1, CYP4F2, CA3 | LMNA 2871/4885CA12 60/4885CA1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.