Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
| ▸ | CA9 | Q16790 | 7/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608057 | 0.97 | THRB (0.35) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL19809168 | 0.93 | NR5A1 (0.32) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL11208189 | 0.90 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL11349951 | 0.90 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL10008072 | 0.90 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL28924404 | 0.90 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL11354124 | 0.90 | THRB (0.40) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL429480 | 0.90 | ADRB2 (0.39) | THRBTSHRNR5A1CA1CA2 | |
| SCHEMBL19809136 | 0.88 | CA1 (0.32) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL707190 | 0.87 | ADRB2 (0.38) | TSHRNR5A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017734-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING CARBON BLACK, METHOD FOR PREPARING THE SAME AND METHOD FOR CURING THE COMPOSITIONS | SWS Silicones Corporation (US) | 1983-04-13 | — | — | EP | disclosed |
| EP-0002745-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING TITANIUM ESTERS | SWS Silicones Corporation (US) | 1981-11-25 | — | — | EP | disclosed |
| EP-0017734-A1 | Curable organopolysiloxane compositions containing carbon black, method for preparing the same and method for curing the compositions | SWS Silicones Corporation (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4221693-A | ROOM TEMPERATURE VULCANIZED SILICONE RUBBERS | WACKER SILICONES CORPORATION | 1980-09-09 | — | — | US | disclosed |
| EP-0002745-A1 | Curable organopolysiloxane compositions containing titanium esters | SWS Silicones Corporation (US) | 1979-07-11 | — | — | EP | disclosed |
| US-4111890-A | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING TITANIUM ESTERS | SWS SILICONES CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |