Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295821 | 0.93 | TSHR (0.40) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1886639 | 0.90 | — | — | |
| Ethylene Glycol SCHEMBL10549545 | 0.88 | MEN1 (0.50) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5598986 | 0.83 | THRB (0.43) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL7176815 | 0.80 | THRB (0.44) | TSHRALDH1A1MEN1KMT2ATHRB | |
| Ethylene Glycol SCHEMBL3404212 | 0.76 | TSHR (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL1629409 | 0.74 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2789915 | 0.74 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10949097 | 0.74 | SMN1; SMN2 (0.32) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| Ether SCHEMBL22443615 | 0.73 | ALDH1A1 (0.42) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089913-A1 | Unsaturated polyester and process for making an unsaturated polyester | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-09-28 | — | — | EP | disclosed |