Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204589 | 0.88 | MAPT (0.35) | ALDH1A1MAPTPKMTDP1NPC1 | |
| SCHEMBL11411623 | 0.84 | MEN1 (0.38) | ALDH1A1MAPTTDP1SMN1; SMN2HTT | |
| SCHEMBL11199866 | 0.81 | MAPT (0.33) | ALDH1A1MAPTPKMTDP1NPC1 | |
| SCHEMBL11288556 | 0.80 | MAPT (0.34) | ALDH1A1MAPTTDP1NPC1SMN1; SMN2 | |
| SCHEMBL11287905 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTTDP1SMN1; SMN2HTT | |
| SCHEMBL11295140 | 0.79 | ALDH1A1 (0.33) | ALDH1A1MAPTTDP1SMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL10854582 | 0.79 | MAPT (0.33) | ALDH1A1MAPTTDP1NPC1SMN1; SMN2 | |
| SCHEMBL10947425 | 0.79 | GPR35 (0.39) | ALDH1A1MAPTTDP1SMN1; SMN2HTT | |
| SCHEMBL11202097 | 0.79 | MAPT (0.34) | ALDH1A1MAPTTDP1LMNAMEN1 | |
| SCHEMBL10766268 | 0.79 | TDP1 (0.42) | ALDH1A1MAPTTDP1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078536-A2 | Phosphinates and phosphonates and their use in the control of weeds | SANDOZ AG (CH) | 1983-05-11 | — | — | EP | disclosed |