Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.54 |
| ▸ | CASP1 | P29466 | 4/20 | 0.54 |
| ▸ | CASP7 | P55210 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.46 |
| ▸ | ALDH1B1 | P30837 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814144 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL15472024 | 0.72 | PRKD1 (0.71) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL14134400 | 0.68 | ALDH2 (0.64) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL7532636 | 0.68 | ALDH1A1 (0.67) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL14514720 | 0.68 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL9920600 | 0.67 | PRKD1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL9920464 | 0.66 | PRKD1 (1.00) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL7534558 | 0.64 | MAOA (0.49) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL9218832 | 0.63 | NQO1 (0.48) | ALDH1A1KDM4EHSD17B10HPGDCASP1 | |
| SCHEMBL17717500 | 0.63 | ATM (1.00) | ALDH1A1KDM4EHSD17B10HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087280-A2 | 3-(2-Mono-and dialkylamino)propyl(-1,2,3,4-tetrahydro-5H-(1) benzopyrano(3,4-c)pyridin-5-ones and derivatives thereof, a process for their production, and pharmaceutical compositions containing such compounds | WARNER-LAMBERT COMPANY (US) | 1983-08-31 | — | — | EP | disclosed |