SCHEMBL7532636

SCHEMBL7532636

Cc1ccc2c3c(c(=O)oc2c1)CCCC3

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.67
KDM4E B2RXH2 6/20 0.67
HPGD P15428 6/20 0.67
HSD17B10 Q99714 6/20 0.67
TSHR P16473 5/20 0.67
GLA P06280 1/20 0.67
GAA P10253 1/20 0.67
CASP1 P29466 1/20 0.67
CASP7 P55210 1/20 0.67
CYP1A2 P05177 1/20 0.65
MAOA P21397 1/20 0.62
ALDH1A2 O94788 2/20 0.59
ALDH2 P05091 2/20 0.59
ALDH1B1 P30837 2/20 0.59
MAPT P10636 2/20 0.58
MAPK1 P28482 2/20 0.58
DRD2 P14416 2/20 0.56
DRD4 P21917 2/20 0.56
STS P08842 7/20 0.56
MEN1 O00255 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8581275 0.81 DRD2 (0.50) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL7534558 0.81 MAOA (0.49) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL21587877 0.81 KDM4E (0.69) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL21140708 0.81 MAOA (0.53) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL9725288 0.80 KDM4E (0.67) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL30465069 0.80 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL3768560 0.80 KDM4E (1.00) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL4710494 0.80 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL3625077 0.79 CYP1A2 (1.00) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL3762769 0.79 CYP1A2 (1.00) ALDH1A1KDM4EHPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002028183-A1 FUNGICIDES SYNGENTA LIMITED (GB) 2002-04-11 WO disclosed